Renal impairment after spontaneous bacterial peritonitis
Spontaneous bacterial peritonitis (SBP) is an important clinical complication affecting patients with cirrhosis and ascites. It is associated with a poor short term and long term prognosis, with an...
View ArticleRenal impairment after spontaneous bacterial peritonitis: MATERIALS AND...
All patients with cirrhosis and ascites admitted to Santa Casa de Misericordia de Porto Alegre, Brazil, from January 1991 to June 2000 were evaluated. A total of 520 patients (1030 hospitalizations)...
View ArticleRenal impairment after spontaneous bacterial peritonitis: MATERIALS AND...
A diagnosis of SBP was established when the ascitic fluid polymorphonuclear cell count was equal to or greater than 250 cells/mm3, independently of bacteriological results. Secondary peritonitis was...
View ArticleRenal impairment after spontaneous bacterial peritonitis: RESULTS (Part 1)
The following variables were assessed as possible predictors of steady or progressive SBP-related RI: BUN and creatinine levels before the diagnosis of SBP, type of infection, antibiotic prophylaxis,...
View ArticleRenal impairment after spontaneous bacterial peritonitis: RESULTS (Part 2)
Some clinical characteristics of patients with or without renal impairment are demonstrated in Table 2. They are similar in these two groups (P>0.05). The overall hospital mortality was 22.9% (25...
View ArticleRenal impairment after spontaneous bacterial peritonitis: RESULTS (Part 3)
The comparison between SBP episodes without RI and with steady or progressive RI revealed that seven of the 17 variables assessed were significant predictors of RI according to the univariate analysis:...
View ArticleRenal impairment after spontaneous bacterial peritonitis: DISCUSSION (Part 1)
Follo et al, studying 252 SBP episodes in 197 patients, demonstrated that approximately 30% presented with RI, which was progressive in 42%, steady in 33% and transient in 25% of the cases. According...
View ArticleRenal impairment after spontaneous bacterial peritonitis: DISCUSSION (Part 2)
The exact pathogenesis of this renal function impairment remains uncertain. Navasa et al, studying 52 patients with cirrhosis and SBP, observed high levels of cytokine (tumour necrosis factor and...
View ArticleRenal impairment after spontaneous bacterial peritonitis: DISCUSSION (Part 3)
The incidence of RI observed in the present study was slightly higher than that observed in the literature, although most authors do not consider cases of transient failure as cases of RI. When our...
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